1lxc: Difference between revisions

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[[Image:1lxc.gif|left|200px]]
[[Image:1lxc.gif|left|200px]]


{{Structure
<!--
|PDB= 1lxc |SIZE=350|CAPTION= <scene name='initialview01'>1lxc</scene>, resolution 2.4&Aring;
The line below this paragraph, containing "STRUCTURE_1lxc", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=AYM:3-(6-AMINOPYRIDIN-3-YL)-N-METHYL-N-[(1-METHYL-1H-INDOL-2-YL)METHYL]ACRYLAMIDE'>AYM</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1lxc| PDB=1lxc  | SCENE= }}  
|RELATEDENTRY=[[1c14|1C14]], [[1i2z|1I2Z]], [[1i30|1I30]], [[1qg6|1QG6]], [[1lx6|1LX6]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lxc OCA], [http://www.ebi.ac.uk/pdbsum/1lxc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1lxc RCSB]</span>
}}


'''Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Acrylamide Inhibitor'''
'''Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Acrylamide Inhibitor'''
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==Reference==
==Reference==
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI)., Miller WH, Seefeld MA, Newlander KA, Uzinskas IN, Burgess WJ, Heerding DA, Yuan CC, Head MS, Payne DJ, Rittenhouse SF, Moore TD, Pearson SC, Berry V, DeWolf WE Jr, Keller PM, Polizzi BJ, Qiu X, Janson CA, Huffman WF, J Med Chem. 2002 Jul 18;45(15):3246-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12109908 12109908]
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI)., Miller WH, Seefeld MA, Newlander KA, Uzinskas IN, Burgess WJ, Heerding DA, Yuan CC, Head MS, Payne DJ, Rittenhouse SF, Moore TD, Pearson SC, Berry V, DeWolf WE Jr, Keller PM, Polizzi BJ, Qiu X, Janson CA, Huffman WF, J Med Chem. 2002 Jul 18;45(15):3246-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12109908 12109908]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Uzinskas, I N.]]
[[Category: Uzinskas, I N.]]
[[Category: Yuan, C C.K.]]
[[Category: Yuan, C C.K.]]
[[Category: enoyl reductase]]
[[Category: Enoyl reductase]]
[[Category: fabi]]
[[Category: Fabi]]
[[Category: oxidoreductase]]
[[Category: Oxidoreductase]]
 
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