1qf4: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qf4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QF4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qf4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QF4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=RPD:(C8-R)-HYDANTOCIDIN+5-PHOSPHATE'>RPD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=RPD:(C8-R)-HYDANTOCIDIN+5-PHOSPHATE'>RPD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf4 OCA], [https://pdbe.org/1qf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qf4 RCSB], [https://www.ebi.ac.uk/pdbsum/1qf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qf4 OCA], [https://pdbe.org/1qf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qf4 RCSB], [https://www.ebi.ac.uk/pdbsum/1qf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qf4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PURA_ECOLI PURA_ECOLI]] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).[HAMAP-Rule:MF_00011]  
[https://www.uniprot.org/uniprot/PURA_ECOLI PURA_ECOLI] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).[HAMAP-Rule:MF_00011]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Adenylosuccinate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chemla, P]]
[[Category: Chemla P]]
[[Category: Cowan-Jacob, S W]]
[[Category: Cowan-Jacob SW]]
[[Category: Fonne-Pfister, R]]
[[Category: Fonne-Pfister R]]
[[Category: Gohda, K]]
[[Category: Gohda K]]
[[Category: Hanessian, S]]
[[Category: Hanessian S]]
[[Category: Lu, P P]]
[[Category: Lu P-P]]
[[Category: Prade, L]]
[[Category: Prade L]]
[[Category: Sanceau, J Y]]
[[Category: Sanceau J-Y]]
[[Category: Gtp-binding]]
[[Category: Gtp-hydrolysing enzyme]]
[[Category: Ligase]]
[[Category: Purine biosynthesis]]
[[Category: Synthetase]]
Retrieved from "https://proteopedia.org/1qf4"