1m6f: Difference between revisions

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[[Image:1m6f.gif|left|200px]]
[[Image:1m6f.gif|left|200px]]


{{Structure
<!--
|PDB= 1m6f |SIZE=350|CAPTION= <scene name='initialview01'>1m6f</scene>, resolution 1.78&Aring;
The line below this paragraph, containing "STRUCTURE_1m6f", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=CGQ:3-[C-[N&#39;-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM'>CGQ</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY=  
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1m6f| PDB=1m6f  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m6f OCA], [http://www.ebi.ac.uk/pdbsum/1m6f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1m6f RCSB]</span>
}}


'''Strong Binding in the DNA Minor Groove by an Aromatic Diamidine With a Shape That Does Not Match the Curvature of the Groove'''
'''Strong Binding in the DNA Minor Groove by an Aromatic Diamidine With a Shape That Does Not Match the Curvature of the Groove'''
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==About this Structure==
==About this Structure==
1M6F is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M6F OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M6F OCA].  


==Reference==
==Reference==
Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove., Nguyen B, Lee MP, Hamelberg D, Joubert A, Bailly C, Brun R, Neidle S, Wilson WD, J Am Chem Soc. 2002 Nov 20;124(46):13680-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12431090 12431090]
Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove., Nguyen B, Lee MP, Hamelberg D, Joubert A, Bailly C, Brun R, Neidle S, Wilson WD, J Am Chem Soc. 2002 Nov 20;124(46):13680-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12431090 12431090]
[[Category: Protein complex]]
[[Category: Bailly, C.]]
[[Category: Bailly, C.]]
[[Category: Brun, R.]]
[[Category: Brun, R.]]
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[[Category: Nguyen, B.]]
[[Category: Nguyen, B.]]
[[Category: Wilson, W D.]]
[[Category: Wilson, W D.]]
[[Category: dna-drug complex]]
[[Category: Dna-drug complex]]
[[Category: double helix]]
[[Category: Double helix]]
[[Category: minor groove binder]]
[[Category: Minor groove binder]]
[[Category: nucleic acid]]
[[Category: Nucleic acid]]
 
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