1tqq: Difference between revisions
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<StructureSection load='1tqq' size='340' side='right'caption='[[1tqq]], [[Resolution|resolution]] 2.75Å' scene=''> | <StructureSection load='1tqq' size='340' side='right'caption='[[1tqq]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tqq]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1tqq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TQQ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tqq OCA], [https://pdbe.org/1tqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tqq RCSB], [https://www.ebi.ac.uk/pdbsum/1tqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tqq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TOLC_ECOLI TOLC_ECOLI] Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells.<ref>PMID:6337123</ref> <ref>PMID:11274125</ref> <ref>PMID:15228545</ref> <ref>PMID:18955484</ref> <ref>PMID:23176499</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Edwards | [[Category: Edwards PC]] | ||
[[Category: Eswaran | [[Category: Eswaran J]] | ||
[[Category: Higgins | [[Category: Higgins MK]] | ||
[[Category: Hughes | [[Category: Hughes C]] | ||
[[Category: Koronakis | [[Category: Koronakis V]] | ||
[[Category: Schertler | [[Category: Schertler GF]] | ||