2ahc: Difference between revisions

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<StructureSection load='2ahc' size='340' side='right'caption='[[2ahc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2ahc' size='340' side='right'caption='[[2ahc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ahc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ahc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AHC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VNL:4-HYDROXY-3-METHOXYBENZOATE'>VNL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tt8|1tt8]], [[1xlr|1xlr]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VNL:4-HYDROXY-3-METHOXYBENZOATE'>VNL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ubiC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chorismate_lyase Chorismate lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.40 4.1.3.40] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ahc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahc OCA], [https://pdbe.org/2ahc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ahc RCSB], [https://www.ebi.ac.uk/pdbsum/2ahc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ahc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ahc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahc OCA], [https://pdbe.org/2ahc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ahc RCSB], [https://www.ebi.ac.uk/pdbsum/2ahc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ahc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UBIC_ECOLI UBIC_ECOLI]] Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.[HAMAP-Rule:MF_01632]  
[https://www.uniprot.org/uniprot/UBIC_ECOLI UBIC_ECOLI] Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.[HAMAP-Rule:MF_01632]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Chorismate lyase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gallagher, D T]]
[[Category: Gallagher DT]]
[[Category: Smith, N N]]
[[Category: Smith NN]]
[[Category: 123654 antiparallel sheet]]
[[Category: Internal active site]]
[[Category: Lyase]]
[[Category: Ubiquinone pathway]]
[[Category: Unique fold]]
Retrieved from "https://proteopedia.org/2ahc"