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<StructureSection load='2xqn' size='340' side='right'caption='[[2xqn]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
<StructureSection load='2xqn' size='340' side='right'caption='[[2xqn]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xqn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xqn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2iyb|2iyb]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqn OCA], [https://pdbe.org/2xqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xqn RCSB], [https://www.ebi.ac.uk/pdbsum/2xqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xqn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqn OCA], [https://pdbe.org/2xqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xqn RCSB], [https://www.ebi.ac.uk/pdbsum/2xqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xqn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TES_HUMAN TES_HUMAN]] Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.<ref>PMID:11420696</ref> <ref>PMID:12695497</ref> <ref>PMID:12571287</ref>  [[https://www.uniprot.org/uniprot/ENAH_HUMAN ENAH_HUMAN]] Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation (By similarity).<ref>PMID:11696321</ref> <ref>PMID:18158903</ref> 
[https://www.uniprot.org/uniprot/ACL7A_HUMAN ACL7A_HUMAN]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 2xqn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2xqn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Briggs, D C]]
[[Category: Briggs DC]]
[[Category: Knowles, P P]]
[[Category: Knowles PP]]
[[Category: McDonald, N Q]]
[[Category: McDonald NQ]]
[[Category: Murray-Rust, J]]
[[Category: Murray-Rust J]]
[[Category: Acrosome]]
[[Category: Cytoskeleton]]
[[Category: Focal adhesion]]
[[Category: Metal binding protein]]
[[Category: Metal-binding protein]]
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