2y7q: Difference between revisions
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<StructureSection load='2y7q' size='340' side='right'caption='[[2y7q]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='2y7q' size='340' side='right'caption='[[2y7q]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y7q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2y7q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y7Q FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7q OCA], [https://pdbe.org/2y7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7q RCSB], [https://www.ebi.ac.uk/pdbsum/2y7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7q ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7q OCA], [https://pdbe.org/2y7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7q RCSB], [https://www.ebi.ac.uk/pdbsum/2y7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Beavil | [[Category: Beavil AJ]] | ||
[[Category: Davies | [[Category: Davies AM]] | ||
[[Category: Holdom | [[Category: Holdom MD]] | ||
[[Category: Nettleship | [[Category: Nettleship JE]] | ||
[[Category: Owens | [[Category: Owens RJ]] | ||
[[Category: Sutton | [[Category: Sutton BJ]] | ||
Latest revision as of 08:09, 23 August 2023
THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI
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