2yba: Difference between revisions

<table><tr><td colspan='2'>[[2yba]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YBA FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>

[https://www.uniprot.org/uniprot/CAF1_DROME CAF1_DROME] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the nucleosome remodeling and deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the nucleosome remodeling factor (NURF) complex, which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin; and the polycomb group (PcG) repressor complex ESC-E(Z), which promotes repression of homeotic genes during development. Also required for transcriptional repression of E2F target genes by E2f2 and Rbf or Rbf2.<ref>PMID:8887645</ref> <ref>PMID:9419341</ref> <ref>PMID:9784495</ref> <ref>PMID:12490953</ref> <ref>PMID:15456884</ref>  

[[Category: Drosophila melanogaster]]

[[Category: Aiwazian J]]

[[Category: Bauer A]]

[[Category: Bouwmeester T]]

[[Category: Bunker RD]]

[[Category: Chan H]]

[[Category: Faty M]]

[[Category: Fischle W]]

[[Category: Gu J]]

[[Category: Gut H]]

[[Category: Hess D]]

[[Category: Li L]]

[[Category: Lingaraju GM]]

[[Category: Ly-Hartig N]]

[[Category: Muller J]]

[[Category: Prusty AB]]

[[Category: Sack R]]

[[Category: Schmitges FW]]

[[Category: Stutzer A]]

[[Category: Thoma NH]]

[[Category: Wirth U]]

[[Category: Zhao K]]

[[Category: Zhou S]]