8ihk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8ihk is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of HCA3-Gi complex with acifran (local)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8ihk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IHK OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8IHK FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9X:(5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic+acid'>P9X</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8ihk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ihk OCA], [https://pdbe.org/8ihk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ihk RCSB], [https://www.ebi.ac.uk/pdbsum/8ihk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ihk ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/HCAR3_HUMAN HCAR3_HUMAN] Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.<ref>PMID:12522134</ref> <ref>PMID:19561068</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Escherichia coli]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Fujiyoshi Y]]

[[Category: Nishikawa K]]

[[Category: Suzuki H]]

[[Category: Suzuki S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8ihk is ON HOLD  until Paper Publication
+==Cryo-EM structure of HCA3-Gi complex with acifran (local)==
+<StructureSection load='8ihk' size='340' side='right'caption='[[8ihk]], [[Resolution|resolution]] 3.21&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ihk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IHK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IHK FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.21&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9X:(5~{S})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic+acid'>P9X</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ihk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ihk OCA], [https://pdbe.org/8ihk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ihk RCSB], [https://www.ebi.ac.uk/pdbsum/8ihk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ihk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/HCAR3_HUMAN HCAR3_HUMAN] Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.<ref>PMID:12522134</ref> <ref>PMID:19561068</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Fujiyoshi Y]]
+[[Category: Nishikawa K]]
+[[Category: Suzuki H]]
+[[Category: Suzuki S]]