2gao: Difference between revisions
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<StructureSection load='2gao' size='340' side='right'caption='[[2gao]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2gao' size='340' side='right'caption='[[2gao]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2gao]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2gao]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GAO FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gao OCA], [https://pdbe.org/2gao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gao RCSB], [https://www.ebi.ac.uk/pdbsum/2gao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gao ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gao FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gao OCA], [https://pdbe.org/2gao PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gao RCSB], [https://www.ebi.ac.uk/pdbsum/2gao PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gao ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SAR1A_HUMAN SAR1A_HUMAN] Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).<ref>PMID:17005010</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Dimov | [[Category: Dimov S]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Park | [[Category: Park H]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | [[Category: Tempel W]] | ||
[[Category: Tempel | [[Category: Wang J]] | ||
[[Category: Wang | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Yaniw D]] | ||
[[Category: Yaniw | |||
Latest revision as of 09:38, 30 August 2023
Crystal Structure of Human SAR1a in Complex With GDP
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