2gt4: Difference between revisions

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<StructureSection load='2gt4' size='340' side='right'caption='[[2gt4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2gt4' size='340' side='right'caption='[[2gt4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gt4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GT4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gt4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GT4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GDD:GUANOSINE-5-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rya|1rya]], [[2gt2|2gt2]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GDD:GUANOSINE-5-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yefc ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gt4 OCA], [https://pdbe.org/2gt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gt4 RCSB], [https://www.ebi.ac.uk/pdbsum/2gt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gt4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gt4 OCA], [https://pdbe.org/2gt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gt4 RCSB], [https://www.ebi.ac.uk/pdbsum/2gt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gt4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GMM_ECOLI GMM_ECOLI]] Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid.<ref>PMID:10913267</ref> <ref>PMID:7592609</ref>
[https://www.uniprot.org/uniprot/GMM_ECOLI GMM_ECOLI] Hydrolyzes both GDP-mannose and GDP-glucose. Could participate in the regulation of cell wall biosynthesis by influencing the concentration of GDP-mannose or GDP-glucose in the cell. Might also be involved in the biosynthesis of the slime polysaccharide colanic acid.<ref>PMID:10913267</ref> <ref>PMID:7592609</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Amzel, L A]]
[[Category: Amzel LA]]
[[Category: Azurmendi, H F]]
[[Category: Azurmendi HF]]
[[Category: Bianchet, M A]]
[[Category: Bianchet MA]]
[[Category: Gabelli, S B]]
[[Category: Gabelli SB]]
[[Category: Mildvan, A S]]
[[Category: Mildvan AS]]
[[Category: Gdp-mannose hydrolase gdp-glucose hydrolase nudix gdp gdp-fucose]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/2gt4"