2p0r: Difference between revisions

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<StructureSection load='2p0r' size='340' side='right'caption='[[2p0r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2p0r' size='340' side='right'caption='[[2p0r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2p0r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0R FirstGlance]. <br>
<table><tr><td colspan='2'>[[2p0r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Streptomyces_roseus Streptomyces roseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR7:AMINO{[(4S)-4-AMINO-5,5-DIHYDROXYPENTYL]AMINO}METHANIMINIUM'>AR7</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR7:AMINO{[(4S)-4-AMINO-5,5-DIHYDROXYPENTYL]AMINO}METHANIMINIUM'>AR7</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ziv|1ziv]], [[2nqa|2nqa]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAPN9, NCL4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Calpain-1 Calpain-1], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.52 3.4.22.52] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0r OCA], [https://pdbe.org/2p0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0r RCSB], [https://www.ebi.ac.uk/pdbsum/2p0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0r OCA], [https://pdbe.org/2p0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0r RCSB], [https://www.ebi.ac.uk/pdbsum/2p0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CAN9_HUMAN CAN9_HUMAN]] Calcium-regulated non-lysosomal thiol-protease.  
[https://www.uniprot.org/uniprot/CAN9_HUMAN CAN9_HUMAN] Calcium-regulated non-lysosomal thiol-protease.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Calpain-1]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Streptomyces roseus]]
[[Category: Bochkarev, A]]
[[Category: Arrowsmith CH]]
[[Category: Butler-Cole, C]]
[[Category: Bochkarev A]]
[[Category: Davis, T L]]
[[Category: Butler-Cole C]]
[[Category: Dhe-Paganon, S]]
[[Category: Davis TL]]
[[Category: Edwards, A M]]
[[Category: Dhe-Paganon S]]
[[Category: Finerty, P J]]
[[Category: Edwards AM]]
[[Category: Paramanathan, R]]
[[Category: Finerty Jr PJ]]
[[Category: Structural genomic]]
[[Category: Paramanathan R]]
[[Category: Sundstrom, M]]
[[Category: Sundstrom M]]
[[Category: Walker, J R]]
[[Category: Walker JR]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Alpha-beta protein]]
[[Category: Calcium-dependent enzyme]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor complex]]
[[Category: Sgc]]
Retrieved from "https://proteopedia.org/2p0r"