2p86: Difference between revisions

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<StructureSection load='2p86' size='340' side='right'caption='[[2p86]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
<StructureSection load='2p86' size='340' side='right'caption='[[2p86]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2p86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P86 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2p86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P86 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=VS1:3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5-+PHENYL-PENTANE-1-SULFONYLBENZENE'>VS1</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2p7u|2p7u]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=VS1:3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5-+PHENYL-PENTANE-1-SULFONYLBENZENE'>VS1</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rhodesain ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31286 TRYBR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cathepsin_L Cathepsin L], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.15 3.4.22.15] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p86 OCA], [https://pdbe.org/2p86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p86 RCSB], [https://www.ebi.ac.uk/pdbsum/2p86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p86 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p86 OCA], [https://pdbe.org/2p86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p86 RCSB], [https://www.ebi.ac.uk/pdbsum/2p86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p86 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q95PM0_TRYBR Q95PM0_TRYBR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cathepsin L]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Trybr]]
[[Category: Trypanosoma brucei rhodesiense]]
[[Category: Brinen, L S]]
[[Category: Brinen LS]]
[[Category: Marion, R]]
[[Category: Marion R]]
[[Category: Cysteine protease]]
[[Category: Hydrolase]]
[[Category: Neglected disease]]
[[Category: Trypanosoma brucei]]