2pmd: Difference between revisions

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<StructureSection load='2pmd' size='340' side='right'caption='[[2pmd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='2pmd' size='340' side='right'caption='[[2pmd]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pmd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PMD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pmd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PMD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2aho|2aho]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eif2g ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmd OCA], [https://pdbe.org/2pmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pmd RCSB], [https://www.ebi.ac.uk/pdbsum/2pmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pmd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmd OCA], [https://pdbe.org/2pmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pmd RCSB], [https://www.ebi.ac.uk/pdbsum/2pmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pmd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).  
[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 35091]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blaesi, U]]
[[Category: Saccharolobus solfataricus]]
[[Category: Fedorov, R V]]
[[Category: Blaesi U]]
[[Category: Garber, M B]]
[[Category: Fedorov RV]]
[[Category: Hasenohrl, D]]
[[Category: Garber MB]]
[[Category: Manstein, D J]]
[[Category: Hasenohrl D]]
[[Category: Nikonov, O S]]
[[Category: Manstein DJ]]
[[Category: Nikonov, S V]]
[[Category: Nikonov OS]]
[[Category: Nikulin, A D]]
[[Category: Nikonov SV]]
[[Category: Stolboushkina, E A]]
[[Category: Nikulin AD]]
[[Category: Aif2]]
[[Category: Stolboushkina EA]]
[[Category: Gdp]]
[[Category: Gdpnp]]
[[Category: Initiation factor 2 gamma subunit]]
[[Category: Initiation of the translation]]
[[Category: Nucleotide binding]]
[[Category: Pyrophosphate]]
[[Category: Translation]]