2qbo: Difference between revisions

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<StructureSection load='2qbo' size='340' side='right'caption='[[2qbo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2qbo' size='340' side='right'caption='[[2qbo]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2qbo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QBO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2qbo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QBO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAM:CAMPHOR'>CAM</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qbl|2qbl]], [[2qbn|2qbn]], [[2qbm|2qbm]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAM:CAMPHOR'>CAM</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">camC, cyp101 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qbo OCA], [https://pdbe.org/2qbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qbo RCSB], [https://www.ebi.ac.uk/pdbsum/2qbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qbo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qbo OCA], [https://pdbe.org/2qbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qbo RCSB], [https://www.ebi.ac.uk/pdbsum/2qbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qbo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU]] Involved in a camphor oxidation system.  
[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU] Involved in a camphor oxidation system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens putidus flugge 1886]]
[[Category: Camphor 5-monooxygenase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Koenig, K von]]
[[Category: Pseudomonas putida]]
[[Category: Makris, T M]]
[[Category: Makris TM]]
[[Category: Schlichting, I]]
[[Category: Schlichting I]]
[[Category: Sligar, S D]]
[[Category: Sligar SD]]
[[Category: Conserved active site residue]]
[[Category: Von Koenig K]]
[[Category: Cyanide complex]]
[[Category: Cyp101]]
[[Category: Gly248]]
[[Category: Heme geometry]]
[[Category: Mutant]]
[[Category: Oxidoreductase]]

Revision as of 11:28, 30 August 2023

Crystal structure of the P450cam G248V mutant in the cyanide bound state

2qbo, resolution 1.90Å

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