2qq2: Difference between revisions
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<StructureSection load='2qq2' size='340' side='right'caption='[[2qq2]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='2qq2' size='340' side='right'caption='[[2qq2]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2qq2]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2qq2]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QQ2 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qq2 OCA], [https://pdbe.org/2qq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2qq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qq2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qq2 OCA], [https://pdbe.org/2qq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2qq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qq2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/BACH_HUMAN BACH_HUMAN] Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Arrowsmith | [[Category: Berglund H]] | ||
[[Category: Busam R]] | |||
[[Category: Berglund | [[Category: Collins R]] | ||
[[Category: Busam | [[Category: Dahlgren LG]] | ||
[[Category: Collins | [[Category: Edwards A]] | ||
[[Category: Dahlgren | [[Category: Flodin S]] | ||
[[Category: Edwards | [[Category: Flores A]] | ||
[[Category: Flodin | [[Category: Graslund S]] | ||
[[Category: Flores | [[Category: Hallberg BM]] | ||
[[Category: Graslund | [[Category: Hammarstrom M]] | ||
[[Category: Hallberg | [[Category: Herman MD]] | ||
[[Category: Hammarstrom | [[Category: Holmberg-Schiavone L]] | ||
[[Category: Herman | [[Category: Johansson I]] | ||
[[Category: Holmberg-Schiavone | [[Category: Kallas A]] | ||
[[Category: Johansson | [[Category: Karlberg T]] | ||
[[Category: Kallas | [[Category: Kotenyova T]] | ||
[[Category: Karlberg | [[Category: Lehtio L]] | ||
[[Category: Kotenyova | [[Category: Moche M]] | ||
[[Category: Lehtio | [[Category: Nordlund P]] | ||
[[Category: Moche | [[Category: Nyman T]] | ||
[[Category: Nordlund | [[Category: Persson C]] | ||
[[Category: Nyman | [[Category: Sagemark J]] | ||
[[Category: Persson | [[Category: Stenmark P]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sagemark | [[Category: Thorsell AG]] | ||
[[Category: Stenmark | [[Category: Tresaugues L]] | ||
[[Category: Sundstrom | [[Category: Weigelt J]] | ||
[[Category: Thorsell | [[Category: Welin M]] | ||
[[Category: Tresaugues | [[Category: Van den Berg S]] | ||
[[Category: Weigelt | |||
[[Category: Welin | |||
[[Category: | |||
Latest revision as of 11:38, 30 August 2023
Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Large Structures
- Arrowsmith CH
- Berglund H
- Busam R
- Collins R
- Dahlgren LG
- Edwards A
- Flodin S
- Flores A
- Graslund S
- Hallberg BM
- Hammarstrom M
- Herman MD
- Holmberg-Schiavone L
- Johansson I
- Kallas A
- Karlberg T
- Kotenyova T
- Lehtio L
- Moche M
- Nordlund P
- Nyman T
- Persson C
- Sagemark J
- Stenmark P
- Sundstrom M
- Thorsell AG
- Tresaugues L
- Weigelt J
- Welin M
- Van den Berg S
