3bpu: Difference between revisions

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<StructureSection load='3bpu' size='340' side='right'caption='[[3bpu]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3bpu' size='340' side='right'caption='[[3bpu]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3bpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BPU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAGI1, BAIAP1, BAP1, TNRC19 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [https://pdbe.org/3bpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [https://www.ebi.ac.uk/pdbsum/3bpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bpu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpu OCA], [https://pdbe.org/3bpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bpu RCSB], [https://www.ebi.ac.uk/pdbsum/3bpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bpu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN]] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).  
[https://www.uniprot.org/uniprot/MAGI1_HUMAN MAGI1_HUMAN] May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Cooper, C]]
[[Category: Cooper C]]
[[Category: Delft, F von]]
[[Category: Doyle DA]]
[[Category: Doyle, D A]]
[[Category: Edwards AM]]
[[Category: Edwards, A M]]
[[Category: Elkins J]]
[[Category: Elkins, J]]
[[Category: Hozjan V]]
[[Category: Hozjan, V]]
[[Category: Oppermann U]]
[[Category: Oppermann, U]]
[[Category: Pike ACW]]
[[Category: Pike, A C.W]]
[[Category: Pilka ES]]
[[Category: Pilka, E S]]
[[Category: Weigelt J]]
[[Category: Structural genomic]]
[[Category: Von Delft F]]
[[Category: Weigelt, J]]
[[Category: Atp-binding]]
[[Category: Cell junction]]
[[Category: Membrane associated guanylate kinase]]
[[Category: Nucleotide-binding]]
[[Category: Pdz]]
[[Category: Phosphoprotein]]
[[Category: Sgc]]
[[Category: Tight junction]]
[[Category: Transferase]]

Latest revision as of 12:12, 30 August 2023

Crystal structure of the 3rd PDZ domain of human membrane associated guanylate kinase, C677S and C709S double mutant

3bpu, resolution 1.60Å

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