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==Nanobody targeting human Vsig4 in Spacegroup P212121==
==Nanobody targeting human Vsig4 in Spacegroup P212121==
<StructureSection load='5iml' size='340' side='right' caption='[[5iml]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5iml' size='340' side='right'caption='[[5iml]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5iml]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelidae Camelidae] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IML OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IML FirstGlance]. <br>
<table><tr><td colspan='2'>[[5iml]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelidae Camelidae] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IML FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5imk|5imk]], [[5imm|5imm]], [[5imo|5imo]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VSIG4, CRIg, Z39IG, UNQ317/PRO362 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iml OCA], [https://pdbe.org/5iml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iml RCSB], [https://www.ebi.ac.uk/pdbsum/5iml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iml ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iml OCA], [http://pdbe.org/5iml PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iml RCSB], [http://www.ebi.ac.uk/pdbsum/5iml PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iml ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VSIG4_HUMAN VSIG4_HUMAN]] Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.<ref>PMID:17016562</ref> <ref>PMID:17051150</ref>
[https://www.uniprot.org/uniprot/VSIG4_HUMAN VSIG4_HUMAN] Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.<ref>PMID:17016562</ref> <ref>PMID:17051150</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Camelidae]]
[[Category: Camelidae]]
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Wen, Y]]
[[Category: Large Structures]]
[[Category: Complement receptor]]
[[Category: Wen Y]]
[[Category: Immune system]]
[[Category: Nanobody]]
[[Category: Vsig4 crig]]
Retrieved from "https://proteopedia.org/5iml"