5ipr: Difference between revisions

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<SX load='5ipr' size='340' side='right' viewer='molstar' caption='[[5ipr]], [[Resolution|resolution]] 14.10&Aring;' scene=''>
<SX load='5ipr' size='340' side='right' viewer='molstar' caption='[[5ipr]], [[Resolution|resolution]] 14.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ipr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IPR FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ipr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IPR FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iou|5iou]], [[5iov|5iov]], [[5ipq|5ipq]], [[5ips|5ips]], [[5ipt|5ipt]], [[5ipu|5ipu]], [[5ipv|5ipv]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14.1&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8355 African clawed frog])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ipr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipr OCA], [https://pdbe.org/5ipr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ipr RCSB], [https://www.ebi.ac.uk/pdbsum/5ipr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ipr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipr OCA], [http://pdbe.org/5ipr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ipr RCSB], [http://www.ebi.ac.uk/pdbsum/5ipr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NMDZ1_XENLA NMDZ1_XENLA] Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:16214956, PubMed:19524674, PubMed:21677647, PubMed:25008524, PubMed:26912815, PubMed:27135925, Ref.11, PubMed:28232581). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).<ref>PMID:16214956</ref> <ref>PMID:19524674</ref> <ref>PMID:21677647</ref> <ref>PMID:25008524</ref> <ref>PMID:26912815</ref> <ref>PMID:27135925</ref> <ref>PMID:28232581</ref> [PDB:5IOV]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</SX>
</SX>
[[Category: African clawed frog]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Goehring, A]]
[[Category: Xenopus laevis]]
[[Category: Gouaux, E]]
[[Category: Goehring A]]
[[Category: Lee, C H]]
[[Category: Gouaux E]]
[[Category: Mchaourab, S H]]
[[Category: Lee CH]]
[[Category: Stein, A R]]
[[Category: Mchaourab SH]]
[[Category: Yoshioka, C]]
[[Category: Stein AR]]
[[Category: Zhu, S]]
[[Category: Yoshioka C]]
[[Category: Ligand-gated ion channel]]
[[Category: Zhu S]]
[[Category: Signaling protein]]
[[Category: Synaptic transmission]]
Retrieved from "https://proteopedia.org/5ipr"