3itk: Difference between revisions

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<StructureSection load='3itk' size='340' side='right'caption='[[3itk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3itk' size='340' side='right'caption='[[3itk]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3itk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ITK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ITK FirstGlance]. <br>
<table><tr><td colspan='2'>[[3itk]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ITK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ITK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2q3e|2q3e]], [[2qg4|2qg4]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGDH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-glucose_6-dehydrogenase UDP-glucose 6-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.22 1.1.1.22] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3itk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3itk OCA], [https://pdbe.org/3itk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3itk RCSB], [https://www.ebi.ac.uk/pdbsum/3itk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3itk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3itk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3itk OCA], [https://pdbe.org/3itk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3itk RCSB], [https://www.ebi.ac.uk/pdbsum/3itk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3itk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UGDH_HUMAN UGDH_HUMAN]] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.  
[https://www.uniprot.org/uniprot/UGDH_HUMAN UGDH_HUMAN] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: UDP-glucose 6-dehydrogenase]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra C]]
[[Category: Bountra, C]]
[[Category: Chaikuad A]]
[[Category: Chaikuad, A]]
[[Category: Edwards AM]]
[[Category: Delft, F von]]
[[Category: Egger S]]
[[Category: Edwards, A M]]
[[Category: Filippakopoulos P]]
[[Category: Egger, S]]
[[Category: Kavanagh KL]]
[[Category: Filippakopoulos, P]]
[[Category: Muniz JRC]]
[[Category: Kavanagh, K L]]
[[Category: Nidetzky B]]
[[Category: Muniz, J R.C]]
[[Category: Oppermann U]]
[[Category: Nidetzky, B]]
[[Category: Sethi R]]
[[Category: Oppermann, U]]
[[Category: Weigelt J]]
[[Category: Structural genomic]]
[[Category: Yue WW]]
[[Category: Sethi, R]]
[[Category: Von Delft F]]
[[Category: Weigelt, J]]
[[Category: Yue, W W]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Phosphoprotein]]
[[Category: Sgc]]
Retrieved from "https://proteopedia.org/3itk"