3ksl: Difference between revisions

<StructureSection load='3ksl' size='340' side='right'caption='[[3ksl]], [[Resolution|resolution]] 2.05&Aring;' scene=''>

<table><tr><td colspan='2'>[[3ksl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KSL FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SZH:(2S,6E)-8-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-2,6-DIMETHYLOCT-6-EN-1-YL+(2S)-3,3,3-TRIFLUORO-2-HYDRAZINOPROPANOATE'>SZH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ksl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ksl OCA], [https://pdbe.org/3ksl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ksl RCSB], [https://www.ebi.ac.uk/pdbsum/3ksl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ksl ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/FNTA_RAT FNTA_RAT] Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity).

*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]

[[Category: Large Structures]]

[[Category: Rattus norvegicus]]

[[Category: DeGraw A]]

[[Category: Distefano MD]]

[[Category: Edelstein RL]]

[[Category: Henry O]]

[[Category: Hovlid ML]]

[[Category: Hruza AW]]

[[Category: Labello NP]]

[[Category: Lenevich S]]

[[Category: Lopez-Gallego F]]

[[Category: Ochocki J]]

[[Category: Schmidt-Dannert C]]

[[Category: Strickland CL]]

[[Category: Talbot T]]

[[Category: Young V]]