3lce: Difference between revisions

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<StructureSection load='3lce' size='340' side='right'caption='[[3lce]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3lce' size='340' side='right'caption='[[3lce]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lce]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3LCE FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lce]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LCE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LCE:(1S,3S,4S,5S)-7,7-DICHLORO-3-METHOXY-2-THIABICYCLO[3.2.0]HEPTAN-6-ONE-4-CARBOXYLIC+ACID'>LCE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=LCE:(1S,3S,4S,5S)-7,7-DICHLORO-3-METHOXY-2-THIABICYCLO[3.2.0]HEPTAN-6-ONE-4-CARBOXYLIC+ACID'>LCE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lce OCA], [https://pdbe.org/3lce PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lce RCSB], [https://www.ebi.ac.uk/pdbsum/3lce PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lce ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3lce FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lce OCA], [http://pdbe.org/3lce PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lce RCSB], [http://www.ebi.ac.uk/pdbsum/3lce PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lce ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI]] Hydrolyzes both carbenicillin and oxacillin.  
[https://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI] Hydrolyzes both carbenicillin and oxacillin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Gretes, M]]
[[Category: Gretes M]]
[[Category: Strynadka, N C.J]]
[[Category: Strynadka NCJ]]
[[Category: Antibiotic resistance]]
[[Category: Beta-lactam mimic]]
[[Category: Beta-lactamase inhibitor]]
[[Category: Cyclobutanone]]
[[Category: Disulfide bond]]
[[Category: Hemiketal]]
[[Category: Hydrolase]]
[[Category: Plasmid]]
[[Category: Transposable element]]
Retrieved from "https://proteopedia.org/3lce"