3lhd: Difference between revisions
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==Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-homocysteine== | ==Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-homocysteine== | ||
<StructureSection load='3lhd' size='340' side='right' caption='[[3lhd]], [[Resolution|resolution]] 2.59Å' scene=''> | <StructureSection load='3lhd' size='340' side='right'caption='[[3lhd]], [[Resolution|resolution]] 2.59Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3lhd]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3lhd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LHD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lhd OCA], [https://pdbe.org/3lhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lhd RCSB], [https://www.ebi.ac.uk/pdbsum/3lhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lhd ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TRMI_PYRAB TRMI_PYRAB] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.<ref>PMID:14739239</ref> <ref>PMID:20483913</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pyrococcus abyssi GE5]] | ||
[[Category: Barbey | [[Category: Barbey C]] | ||
[[Category: Golinelli-Pimpaneau | [[Category: Golinelli-Pimpaneau B]] | ||
[[Category: Guelorget | [[Category: Guelorget A]] | ||
[[Category: Wouters | [[Category: Wouters J]] | ||