3odg: Difference between revisions

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==crystal structure of xanthosine phosphorylase bound with xanthine from Yersinia pseudotuberculosis==
==crystal structure of xanthosine phosphorylase bound with xanthine from Yersinia pseudotuberculosis==
<StructureSection load='3odg' size='340' side='right' caption='[[3odg]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
<StructureSection load='3odg' size='340' side='right'caption='[[3odg]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3odg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudotuberkulosis"_(sic)_pfeiffer_1889 "bacillus pseudotuberkulosis" (sic) pfeiffer 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ODG FirstGlance]. <br>
<table><tr><td colspan='2'>[[3odg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pseudotuberculosis Yersinia pseudotuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ODG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ODG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=XAN:XANTHINE'>XAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pndA, xapA, YPTB1201 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=633 "Bacillus pseudotuberkulosis" (sic) Pfeiffer 1889])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=XAN:XANTHINE'>XAN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3odg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odg OCA], [http://pdbe.org/3odg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3odg RCSB], [http://www.ebi.ac.uk/pdbsum/3odg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3odg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3odg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3odg OCA], [https://pdbe.org/3odg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3odg RCSB], [https://www.ebi.ac.uk/pdbsum/3odg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3odg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q66D48_YERPS Q66D48_YERPS]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477]  
[https://www.uniprot.org/uniprot/Q66D48_YERPS Q66D48_YERPS] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/3odg_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/3odg_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]]
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Almo, S C]]
[[Category: Large Structures]]
[[Category: Burley, S K]]
[[Category: Yersinia pseudotuberculosis]]
[[Category: Kim, J]]
[[Category: Almo SC]]
[[Category: Structural genomic]]
[[Category: Burley SK]]
[[Category: Ramagopal, U A]]
[[Category: Kim J]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: Ramagopal UA]]
[[Category: PSI, Protein structure initiative]]
[[Category: Purine nucleoside binding]]
[[Category: Purine nucleoside phosphorylase]]
[[Category: Transferase]]
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