3p48: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='3p48' size='340' side='right'caption='[[3p48]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
<StructureSection load='3p48' size='340' side='right'caption='[[3p48]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3p48]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P48 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3p48]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P48 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f4f|3f4f]], [[3hhq|3hhq]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUT1, YBR252W, YBR1705 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p48 OCA], [https://pdbe.org/3p48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p48 RCSB], [https://www.ebi.ac.uk/pdbsum/3p48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p48 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p48 OCA], [https://pdbe.org/3p48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p48 RCSB], [https://www.ebi.ac.uk/pdbsum/3p48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p48 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DUT_YEAST DUT_YEAST]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.  
[https://www.uniprot.org/uniprot/DUT_YEAST DUT_YEAST] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: DUTP diphosphatase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: Evdokimova, E]]
[[Category: Evdokimova E]]
[[Category: Kudritska, M]]
[[Category: Kudritska M]]
[[Category: OCSP, Ontario Centre for Structural Proteomics]]
[[Category: Petit P]]
[[Category: Petit, P]]
[[Category: Savchenko A]]
[[Category: Savchenko, A]]
[[Category: Singer AU]]
[[Category: Singer, A U]]
[[Category: Yakunin AF]]
[[Category: Yakunin, A F]]
[[Category: Beta barrel]]
[[Category: Dumppnp pyrophosphatase]]
[[Category: Hydrolase]]
[[Category: Ocsp]]
[[Category: Ontario centre for structural proteomic]]
[[Category: Phosphoprotein]]
[[Category: Structural genomic]]
[[Category: Trimer]]
Retrieved from "https://proteopedia.org/3p48"