5j8e: Difference between revisions

<table><tr><td colspan='2'>[[5j8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J8E FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j8e OCA], [https://pdbe.org/5j8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j8e RCSB], [https://www.ebi.ac.uk/pdbsum/5j8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j8e ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/HOOK3_HUMAN HOOK3_HUMAN] Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.<ref>PMID:11238449</ref> <ref>PMID:17237231</ref> <ref>PMID:18799622</ref>  

[[Category: Homo sapiens]]

[[Category: Ekiert DC]]

[[Category: Schroeder CM]]

[[Category: Vale RD]]