5j8j: Difference between revisions
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<StructureSection load='5j8j' size='340' side='right'caption='[[5j8j]], [[Resolution|resolution]] 2.72Å' scene=''> | <StructureSection load='5j8j' size='340' side='right'caption='[[5j8j]], [[Resolution|resolution]] 2.72Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5j8j]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5j8j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J8J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J8J FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.716Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j8j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j8j OCA], [https://pdbe.org/5j8j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j8j RCSB], [https://www.ebi.ac.uk/pdbsum/5j8j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j8j ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HDA1_YEAST HDA1_YEAST] Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Li | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Shen | [[Category: Li X]] | ||
[[Category: Teng | [[Category: Shen H]] | ||
[[Category: Zhu | [[Category: Teng M]] | ||
[[Category: Zhu Y]] | |||