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==Crystal structure of the HigB2 toxin in complex with Nb2==
==Crystal structure of the HigB2 toxin in complex with Nb2==
<StructureSection load='5ja8' size='340' side='right' caption='[[5ja8]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
<StructureSection load='5ja8' size='340' side='right'caption='[[5ja8]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ja8]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_glama Camelus glama] and [http://en.wikipedia.org/wiki/Vibch Vibch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JA8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ja8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JA8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PDO:1,3-PROPANDIOL'>PDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">higB-2, VC_A0468 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=PDO:1,3-PROPANDIOL'>PDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ja8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ja8 OCA], [http://pdbe.org/5ja8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ja8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ja8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ja8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ja8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ja8 OCA], [https://pdbe.org/5ja8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ja8 RCSB], [https://www.ebi.ac.uk/pdbsum/5ja8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ja8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HIGB2_VIBCH HIGB2_VIBCH]] Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA.  
[https://www.uniprot.org/uniprot/HIGB2_VIBCH HIGB2_VIBCH] Toxic component of a toxin-antitoxin (TA) module. Inhibits translation by cleavage of mRNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus glama]]
[[Category: Lama glama]]
[[Category: Vibch]]
[[Category: Large Structures]]
[[Category: Hadzi, S]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Loris, R]]
[[Category: Hadzi S]]
[[Category: Toxin]]
[[Category: Loris R]]
[[Category: Toxin-antitoxin system]]
Retrieved from "https://proteopedia.org/5ja8"