5jcy: Difference between revisions

<table><tr><td colspan='2'>[[5jcy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JCY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JCY FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYO5A, MYH12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jcy OCA], [http://pdbe.org/5jcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jcy RCSB], [http://www.ebi.ac.uk/pdbsum/5jcy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jcy ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  

[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref> [[http://www.uniprot.org/uniprot/SPIR2_HUMAN SPIR2_HUMAN]] Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.<ref>PMID:21620703</ref> 

[[Category: Human]]

[[Category: Houdusse, A]]

[[Category: Kerkhoff, E]]

[[Category: Malherbes, G]]

[[Category: Pylypenko, O]]

[[Category: Welz, T]]

[[Category: Spir actin nucleator]]