8ec6: Difference between revisions
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==Cryo-EM structure of the Glutaminase C core filament (fGAC)== | |||
<StructureSection load='8ec6' size='340' side='right'caption='[[8ec6]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ec6]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EC6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ec6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ec6 OCA], [https://pdbe.org/8ec6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ec6 RCSB], [https://www.ebi.ac.uk/pdbsum/8ec6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ec6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLSK_MOUSE GLSK_MOUSE] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain.<ref>PMID:16641247</ref> <ref>PMID:22373647</ref> <ref>PMID:22228304</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Ambrosio AL]] | |||
[[Category: Cassago A]] | |||
[[Category: Dias SM]] | |||
[[Category: Islam Z]] | |||
[[Category: Portugal RV]] | |||
[[Category: Quesnay JE]] | |||
[[Category: Rodrigues CT]] | |||
[[Category: Van Heel MG]] | |||