4o75: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4o75]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O75 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4o75]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O75 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2RC:[6-({5-FLUORO-2-[(3,4,5-TRIMETHOXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-PYRIDO[3,2-B][1,4]OXAZIN-4-YL]METHYL+DIHYDROGEN+PHOSPHATE'>2RC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2RC:[6-({5-FLUORO-2-[(3,4,5-TRIMETHOXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-PYRIDO[3,2-B][1,4]OXAZIN-4-YL]METHYL+DIHYDROGEN+PHOSPHATE'>2RC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o75 OCA], [https://pdbe.org/4o75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o75 RCSB], [https://www.ebi.ac.uk/pdbsum/4o75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o75 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o75 OCA], [https://pdbe.org/4o75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o75 RCSB], [https://www.ebi.ac.uk/pdbsum/4o75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o75 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 17:07, 20 September 2023
Crystal structure of the first bromodomain of human BRD4 in complex with FOSTAMATINIB
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