4rv8: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4rv8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RV8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4rv8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RV8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I13:1-(2-{3-[(1E)-N-(2-AMINOETHOXY)ETHANIMIDOYL]PHENYL}PROPAN-2-YL)-3-(4-CHLORO-3-NITROPHENYL)UREA'>I13</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.053&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I13:1-(2-{3-[(1E)-N-(2-AMINOETHOXY)ETHANIMIDOYL]PHENYL}PROPAN-2-YL)-3-(4-CHLORO-3-NITROPHENYL)UREA'>I13</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv8 OCA], [https://pdbe.org/4rv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rv8 RCSB], [https://www.ebi.ac.uk/pdbsum/4rv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rv8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rv8 OCA], [https://pdbe.org/4rv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rv8 RCSB], [https://www.ebi.ac.uk/pdbsum/4rv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rv8 ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 17:56, 20 September 2023

Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum and the inhibitor p131

4rv8, resolution 2.05Å

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