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==Crystal structure of Spindlin1 bound to compound EML631==
==Crystal structure of Spindlin1 bound to compound EML631==
<StructureSection load='5jsj' size='340' side='right' caption='[[5jsj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='5jsj' size='340' side='right'caption='[[5jsj]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jsj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JSJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JSJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jsj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JSJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6PD:[4-(2-PYRROLIDIN-1-YLETHYL)PIPERIDIN-1-YL]-[4-[4-(2-PYRROLIDIN-1-YLETHYL)PIPERIDIN-1-YL]CARBONYL-3-[[4-(PYRROLIDIN-1-YLMETHOXY)PHENYL]AMINO]PHENYL]METHANONE'>6PD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.348&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jsg|5jsg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6PD:[4-(2-PYRROLIDIN-1-YLETHYL)PIPERIDIN-1-YL]-[4-[4-(2-PYRROLIDIN-1-YLETHYL)PIPERIDIN-1-YL]CARBONYL-3-[[4-(PYRROLIDIN-1-YLMETHOXY)PHENYL]AMINO]PHENYL]METHANONE'>6PD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPIN1, OCR, SPIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jsj OCA], [https://pdbe.org/5jsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jsj RCSB], [https://www.ebi.ac.uk/pdbsum/5jsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jsj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jsj OCA], [http://pdbe.org/5jsj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jsj RCSB], [http://www.ebi.ac.uk/pdbsum/5jsj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jsj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).  
[https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5jsj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jsj" style="background-color:#fffaf0;"></div>
==See Also==
*[[Spindlin|Spindlin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Li, H]]
[[Category: Large Structures]]
[[Category: Su, X]]
[[Category: Li H]]
[[Category: Cell cycle]]
[[Category: Su X]]
[[Category: Tudor domain]]

Revision as of 19:04, 20 September 2023

Crystal structure of Spindlin1 bound to compound EML631

5jsj, resolution 2.35Å

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