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==The structure of chaperone SecB in complex with unstructured proPhoA binding site c==
==The structure of chaperone SecB in complex with unstructured proPhoA binding site c==
<StructureSection load='5jtn' size='340' side='right'caption='[[5jtn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='5jtn' size='340' side='right'caption='[[5jtn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5jtn]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57] and [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JTN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JTN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5jtn]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JTN FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jtl|5jtl]], [[5jtm|5jtm]], [[5jtq|5jtq]], [[5jto|5jto]], [[5jtp|5jtp]], [[5jtr|5jtr]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">secB, Z5036, ECs4487 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57]), phoA, b0383, JW0374 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jtn OCA], [https://pdbe.org/5jtn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jtn RCSB], [https://www.ebi.ac.uk/pdbsum/5jtn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jtn ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkaline_phosphatase Alkaline phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.1 3.1.3.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jtn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jtn OCA], [http://pdbe.org/5jtn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jtn RCSB], [http://www.ebi.ac.uk/pdbsum/5jtn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jtn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SECB_ECO57 SECB_ECO57]] One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.  
[https://www.uniprot.org/uniprot/SECB_ECOLI SECB_ECOLI] One of the proteins required for the normal export of some preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. Its substrates include AmpC, DegP, FhuA, FkpA, GBP, LamB, MalE (MBP), OmpA, OmpF, OmpT, OmpX, OppA, PhoE, TolB, TolC, YbgF, YcgK, YgiW and YncE.[HAMAP-Rule:MF_00821]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alkaline phosphatase]]
[[Category: Escherichia coli K-12]]
[[Category: Eco57]]
[[Category: Escherichia coli O157:H7]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Huang, C]]
[[Category: Huang C]]
[[Category: Kalodimos, C G]]
[[Category: Kalodimos CG]]
[[Category: Rossi, P]]
[[Category: Rossi P]]
[[Category: Saio, T]]
[[Category: Saio T]]
[[Category: Chaperone-hydrolase complex]]
[[Category: Molecular chaperone]]
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