8ja7: Difference between revisions

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'''Unreleased structure'''


The entry 8ja7 is ON HOLD  until Paper Publication
==Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose==
 
<StructureSection load='8ja7' size='340' side='right'caption='[[8ja7]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
Authors: Zhang, B., Liang, J., Rao, Z.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ja7]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JA7 FirstGlance]. <br>
Description: Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
[[Category: Zhang, B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ja7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ja7 OCA], [https://pdbe.org/8ja7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ja7 RCSB], [https://www.ebi.ac.uk/pdbsum/8ja7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ja7 ProSAT]</span></td></tr>
[[Category: Liang, J]]
</table>
[[Category: Rao, Z]]
== Function ==
[https://www.uniprot.org/uniprot/SUGA_MYCTU SUGA_MYCTU] Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose. Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M.tuberculosis. Trehalose uptake is essential for virulence. Probably responsible for the translocation of the substrate across the membrane.<ref>PMID:21118978</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Liang J]]
[[Category: Rao Z]]
[[Category: Zhang B]]
Retrieved from "https://proteopedia.org/8ja7"