8tar: Difference between revisions
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==APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD== | |||
<StructureSection load='8tar' size='340' side='right'caption='[[8tar]], [[Resolution|resolution]] 4.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8tar]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TAR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tar OCA], [https://pdbe.org/8tar PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tar RCSB], [https://www.ebi.ac.uk/pdbsum/8tar PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tar ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/APC1_HUMAN APC1_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Amann SJ]] | |||
[[Category: Bodrug T]] | |||
[[Category: Bolhuis DL]] | |||
[[Category: Bonacci T]] | |||
[[Category: Brown NG]] | |||
[[Category: Cui L]] | |||
[[Category: Emanuele MJ]] | |||
[[Category: Grishkovskaya I]] | |||
[[Category: Hahn KM]] | |||
[[Category: Harrison JS]] | |||
[[Category: Haselbach D]] | |||
[[Category: Liu B]] | |||
[[Category: Martinez-Chacin RC]] | |||
[[Category: Paulakonis E]] | |||
[[Category: Pinkin N]] | |||
[[Category: Roscow O]] | |||
[[Category: Steimel JP]] | |||
[[Category: Welsh KA]] | |||
[[Category: Xu P]] | |||
[[Category: Zhang W]] | |||
[[Category: Zhong E]] | |||
Latest revision as of 07:02, 27 September 2023
APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
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