5knj: Difference between revisions

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<StructureSection load='5knj' size='340' side='right'caption='[[5knj]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
<StructureSection load='5knj' size='340' side='right'caption='[[5knj]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5knj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNJ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KNJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5knj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6UX:1-[4-[METHYL-[2-[(3-SULFAMOYLPHENYL)AMINO]PYRIMIDIN-4-YL]AMINO]PHENYL]-3-[4-(TRIFLUOROMETHYLOXY)PHENYL]UREA'>6UX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.88&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ko1|5ko1]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6UX:1-[4-[METHYL-[2-[(3-SULFAMOYLPHENYL)AMINO]PYRIMIDIN-4-YL]AMINO]PHENYL]-3-[4-(TRIFLUOROMETHYLOXY)PHENYL]UREA'>6UX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MLKL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knj OCA], [https://pdbe.org/5knj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knj RCSB], [https://www.ebi.ac.uk/pdbsum/5knj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knj ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5knj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knj OCA], [http://pdbe.org/5knj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knj RCSB], [http://www.ebi.ac.uk/pdbsum/5knj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MLKL_HUMAN MLKL_HUMAN]] Required for the execution of programmed necrosis.<ref>PMID:22265414</ref>
[https://www.uniprot.org/uniprot/MLKL_HUMAN MLKL_HUMAN] Required for the execution of programmed necrosis.<ref>PMID:22265414</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Marcotte, D J]]
[[Category: Marcotte DJ]]
[[Category: Membrane proteins-inhibitor complex]]
[[Category: Pseudokinase domain mlkl compound 1 gfe out type 2 inhibitor]]
Retrieved from "https://proteopedia.org/5knj"