5ko0: Difference between revisions

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<StructureSection load='5ko0' size='340' side='right'caption='[[5ko0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='5ko0' size='340' side='right'caption='[[5ko0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ko0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KO0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ko0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KO0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron crystallography, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5knz|5knz]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ko0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko0 OCA], [https://pdbe.org/5ko0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ko0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ko0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ko0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ko0 OCA], [https://pdbe.org/5ko0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ko0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ko0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ko0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.  
[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cascio, D]]
[[Category: Cascio D]]
[[Category: Eisenberg, D S]]
[[Category: Eisenberg DS]]
[[Category: Gonen, T]]
[[Category: Gonen T]]
[[Category: Hattne, J]]
[[Category: Hattne J]]
[[Category: Krotee, P A.L]]
[[Category: Krotee PAL]]
[[Category: Nannenga, B L]]
[[Category: Nannenga BL]]
[[Category: Reyes, F E]]
[[Category: Reyes FE]]
[[Category: Rodriguez, J A]]
[[Category: Rodriguez JA]]
[[Category: Sawaya, M R]]
[[Category: Sawaya MR]]
[[Category: Shi, D]]
[[Category: Shi D]]
[[Category: Amyloid]]
[[Category: Islet amyloid polypeptide]]
[[Category: Microed]]
[[Category: Protein fibril]]
[[Category: Toxic spine]]
[[Category: Type ii diabetes]]

Revision as of 10:49, 27 September 2023

Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED

5ko0, resolution 1.40Å

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