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<StructureSection load='5kvv' size='340' side='right'caption='[[5kvv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
<StructureSection load='5kvv' size='340' side='right'caption='[[5kvv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5kvv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KVV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KVV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5kvv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KVV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kvu|5kvu]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kvv OCA], [https://pdbe.org/5kvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kvv RCSB], [https://www.ebi.ac.uk/pdbsum/5kvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kvv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kvv OCA], [http://pdbe.org/5kvv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kvv RCSB], [http://www.ebi.ac.uk/pdbsum/5kvv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kvv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MDH_MYCTU MDH_MYCTU]] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01517]  
[https://www.uniprot.org/uniprot/MDH_MYCTU MDH_MYCTU] Catalyzes the reversible oxidation of malate to oxaloacetate.[HAMAP-Rule:MF_01517]


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Malate dehydrogenase]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cheng, Y S]]
[[Category: Cheng YS]]
[[Category: Sacchettini, J C]]
[[Category: Sacchettini JC]]
[[Category: Structural genomic]]
[[Category: Krebs cycle]]
[[Category: Oxidoreductase]]
[[Category: Tbsgc]]

Latest revision as of 10:58, 27 September 2023

Structure of Malate Dehydrogenase in complex with NADH from Mycobacterium tuberculosis

5kvv, resolution 2.01Å

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