5uuy: Difference between revisions

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<StructureSection load='5uuy' size='340' side='right'caption='[[5uuy]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='5uuy' size='340' side='right'caption='[[5uuy]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5uuy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dioclea Dioclea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UUY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5UUY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5uuy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dioclea Dioclea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UUY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5uuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uuy OCA], [http://pdbe.org/5uuy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uuy RCSB], [http://www.ebi.ac.uk/pdbsum/5uuy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uuy ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uuy OCA], [https://pdbe.org/5uuy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uuy RCSB], [https://www.ebi.ac.uk/pdbsum/5uuy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uuy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LECA_DIOVI LECA_DIOVI] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.[REFERENCE:1]<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Dioclea]]
[[Category: Dioclea]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cavada, B S]]
[[Category: Cavada BS]]
[[Category: Fonseca, F M.P]]
[[Category: Fonseca FMP]]
[[Category: Nascimento, K S]]
[[Category: Nascimento KS]]
[[Category: Neco, A H.B]]
[[Category: Neco AHB]]
[[Category: Osterne, V J.S]]
[[Category: Osterne VJS]]
[[Category: Pinto-Junior, V R]]
[[Category: Pinto-Junior VR]]
[[Category: Rocha, C R.C]]
[[Category: Rocha CRC]]
[[Category: Santiago, M Q]]
[[Category: Santiago MQ]]
[[Category: Dioclea lasiocarpa]]
[[Category: Lectin]]
[[Category: Sugar binding protein]]
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