5wiv: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
Line 3: Line 3:
<StructureSection load='5wiv' size='340' side='right'caption='[[5wiv]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='5wiv' size='340' side='right'caption='[[5wiv]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5wiv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WIV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5wiv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WIV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AQD:Nemonapride'>AQD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.143&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wiu|5wiu]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AQD:Nemonapride'>AQD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DRD4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wiv OCA], [https://pdbe.org/5wiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wiv RCSB], [https://www.ebi.ac.uk/pdbsum/5wiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wiv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wiv OCA], [http://pdbe.org/5wiv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wiv RCSB], [http://www.ebi.ac.uk/pdbsum/5wiv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wiv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DRD4_HUMAN DRD4_HUMAN]] Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).  
[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/DRD4_HUMAN DRD4_HUMAN] Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 21:


==See Also==
==See Also==
*[[Dopamine receptor|Dopamine receptor]]
*[[Dopamine receptor 3D structures|Dopamine receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Betz, R M]]
[[Category: Betz RM]]
[[Category: Che, T]]
[[Category: Che T]]
[[Category: Dror, R O]]
[[Category: Dror RO]]
[[Category: Huang, X P]]
[[Category: Huang X-P]]
[[Category: Levit, A]]
[[Category: Levit A]]
[[Category: McCorvy, J D]]
[[Category: McCorvy JD]]
[[Category: Roth, B L]]
[[Category: Roth BL]]
[[Category: Shoichet, B K]]
[[Category: Shoichet BK]]
[[Category: Venkatakrishnan, A J]]
[[Category: Venkatakrishnan AJ]]
[[Category: Wacker, D]]
[[Category: Wacker D]]
[[Category: Wang, S]]
[[Category: Wang S]]
[[Category: Antagonist]]
[[Category: Dopamine receptor]]
[[Category: Gpcr]]
[[Category: Signaling protein-antagonist complex]]
[[Category: Sodium]]
Retrieved from "https://proteopedia.org/5wiv"