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<StructureSection load='6cn0' size='340' side='right'caption='[[6cn0]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<StructureSection load='6cn0' size='340' side='right'caption='[[6cn0]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6cn0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CN0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6CN0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6cn0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CN0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/16S_rRNA_(guanine(1405)-N(7))-methyltransferase 16S rRNA (guanine(1405)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.179 2.1.1.179] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6cn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cn0 OCA], [http://pdbe.org/6cn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cn0 RCSB], [http://www.ebi.ac.uk/pdbsum/6cn0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cn0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cn0 OCA], [https://pdbe.org/6cn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cn0 RCSB], [https://www.ebi.ac.uk/pdbsum/6cn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cn0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RMTC_PROMI RMTC_PROMI]] Specifically methylates the N(7) position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides, including gentamicin and kanamycin.<ref>PMID:16377684</ref> <ref>PMID:20722735</ref>
[https://www.uniprot.org/uniprot/RMTC_PROMI RMTC_PROMI] Specifically methylates the N(7) position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides, including gentamicin and kanamycin.<ref>PMID:16377684</ref> <ref>PMID:20722735</ref>  
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Proteus mirabilis]]
[[Category: Evdokimova, E]]
[[Category: Di Leo R]]
[[Category: Joachimiak, A]]
[[Category: Evdokimova E]]
[[Category: Leo, R Di]]
[[Category: Joachimiak A]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Satchell, K J.F]]
[[Category: Satchell KJF]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Wawrzak, Z]]
[[Category: Wawrzak Z]]
[[Category: Csgid]]
[[Category: Transferase]]

Latest revision as of 15:07, 4 October 2023

2.95 Angstrom Crystal Structure of 16S rRNA Methylase from Proteus mirabilis

6cn0, resolution 2.95Å

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