6dau: Difference between revisions
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<StructureSection load='6dau' size='340' side='right'caption='[[6dau]], [[Resolution|resolution]] 2.26Å' scene=''> | <StructureSection load='6dau' size='340' side='right'caption='[[6dau]], [[Resolution|resolution]] 2.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6dau]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6dau]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor Vibrio cholerae O1 biovar El Tor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DAU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dau OCA], [https://pdbe.org/6dau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dau RCSB], [https://www.ebi.ac.uk/pdbsum/6dau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dau ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ATDA_VIBCH ATDA_VIBCH] Involved in the protection against polyamine toxicity by regulating their concentration. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to the primary amino groups of spermidine to yield N(1)- and N(8)-acetylspermidine. It can use polyamines such as spermine and N(1)-acetylspermine, but not putrescine or cadaverine.<ref>PMID:23184347</ref> <ref>PMID:25623305</ref> | |||
==See Also== | ==See Also== | ||
*[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]] | *[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Vibrio cholerae O1 biovar El Tor]] | ||
[[Category: | [[Category: Anderson WF]] | ||
[[Category: | [[Category: Beahan A]] | ||
[[Category: Filippova | [[Category: Filippova EV]] | ||
[[Category: Joachimiak | [[Category: Joachimiak A]] | ||
[[Category: Kuhn | [[Category: Kuhn ML]] | ||
[[Category: Kulyavtsev | [[Category: Kulyavtsev P]] | ||
[[Category: Minasov | [[Category: Minasov G]] | ||
[[Category: Satchell | [[Category: Satchell KJF]] | ||
[[Category: Tan | [[Category: Tan L]] | ||
[[Category: Tran | [[Category: Tran D]] | ||
Latest revision as of 15:21, 4 October 2023
Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae
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