3ah5: Difference between revisions

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<StructureSection load='3ah5' size='340' side='right'caption='[[3ah5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3ah5' size='340' side='right'caption='[[3ah5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ah5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AH5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ah5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AH5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HP_1533, thyX ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thymidylate_synthase_(FAD) Thymidylate synthase (FAD)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.148 2.1.1.148] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ah5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah5 OCA], [https://pdbe.org/3ah5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ah5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ah5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ah5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ah5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ah5 OCA], [https://pdbe.org/3ah5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ah5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ah5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ah5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/THYX_HELPY THYX_HELPY]] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.  
[https://www.uniprot.org/uniprot/THYX_HELPY THYX_HELPY] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Campylobacter pylori]]
[[Category: Helicobacter pylori 26695]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hu, Y]]
[[Category: Hu Y]]
[[Category: Wang, D]]
[[Category: Wang D]]
[[Category: Zhang, J]]
[[Category: Zhang J]]
[[Category: Zhang, X]]
[[Category: Zhang X]]
[[Category: Zou, Q]]
[[Category: Zou Q]]
[[Category: Dump]]
[[Category: Fad]]
[[Category: Helicobacter pylori]]
[[Category: Thyx]]
[[Category: Transferase]]

Latest revision as of 15:46, 4 October 2023

Crystal Structure of flavin dependent thymidylate synthase ThyX from helicobacter pylori complexed with FAD and dUMP

3ah5, resolution 2.50Å

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