5l8a: Difference between revisions

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<StructureSection load='5l8a' size='340' side='right'caption='[[5l8a]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='5l8a' size='340' side='right'caption='[[5l8a]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5l8a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L8A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5L8A FirstGlance]. <br>
<table><tr><td colspan='2'>[[5l8a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L8A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6RB:1-(2-HYDROXYETHYL)-5-[(4-METHOXYNAPHTHALEN-1-YL)METHYL]-~{N}-(PHENYLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>6RB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w84|2w84]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6RB:1-(2-HYDROXYETHYL)-5-[(4-METHOXYNAPHTHALEN-1-YL)METHYL]-~{N}-(PHENYLMETHYL)-6,7-DIHYDRO-4~{H}-PYRAZOLO[4,3-C]PYRIDINE-3-CARBOXAMIDE'>6RB</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PEX14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l8a OCA], [https://pdbe.org/5l8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l8a RCSB], [https://www.ebi.ac.uk/pdbsum/5l8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l8a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5l8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l8a OCA], [http://pdbe.org/5l8a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l8a RCSB], [http://www.ebi.ac.uk/pdbsum/5l8a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8IEW2_TRYBB Q8IEW2_TRYBB]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Trybb]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Dawidowski, M]]
[[Category: Dawidowski M]]
[[Category: Emmanouilidis, L]]
[[Category: Emmanouilidis L]]
[[Category: Popowicz, G M]]
[[Category: Popowicz GM]]
[[Category: Sattler, M]]
[[Category: Sattler M]]
[[Category: Glycosome]]
[[Category: Inhibitor]]
[[Category: Protein-protein interaction inhibitor]]
[[Category: Signaling protein]]
[[Category: Structure-based drug discovery]]
[[Category: Trypanosomiasis]]
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