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==X-RAY STRUCTURE OF THE METHYLTRANSFERASE SUBUNIT A FROM METHANOTHERMUS FERVIDUS IN COMPLEX WITH COBALAMIN==
==X-RAY STRUCTURE OF THE METHYLTRANSFERASE SUBUNIT A FROM METHANOTHERMUS FERVIDUS IN COMPLEX WITH COBALAMIN==
<StructureSection load='5laa' size='340' side='right' caption='[[5laa]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='5laa' size='340' side='right'caption='[[5laa]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5laa]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Metfv Metfv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LAA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LAA FirstGlance]. <br>
<table><tr><td colspan='2'>[[5laa]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermus_fervidus_DSM_2088 Methanothermus fervidus DSM 2088]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LAA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LAA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtrA, Mfer_0072 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=523846 METFV])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tetrahydromethanopterin_S-methyltransferase Tetrahydromethanopterin S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.86 2.1.1.86] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5laa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5laa OCA], [https://pdbe.org/5laa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5laa RCSB], [https://www.ebi.ac.uk/pdbsum/5laa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5laa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5laa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5laa OCA], [http://pdbe.org/5laa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5laa RCSB], [http://www.ebi.ac.uk/pdbsum/5laa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5laa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/E3GWY7_METFV E3GWY7_METFV]] Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.[HAMAP-Rule:MF_01093]  
[https://www.uniprot.org/uniprot/E3GWY7_METFV E3GWY7_METFV] Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.[HAMAP-Rule:MF_01093]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Metfv]]
[[Category: Large Structures]]
[[Category: Tetrahydromethanopterin S-methyltransferase]]
[[Category: Methanothermus fervidus DSM 2088]]
[[Category: Ermler, U]]
[[Category: Ermler U]]
[[Category: Shima, S]]
[[Category: Shima S]]
[[Category: Wagner, T]]
[[Category: Wagner T]]
[[Category: Cobalamin]]
[[Category: Coenzymem]]
[[Category: Hyperthermophile]]
[[Category: Marine organism]]
[[Category: Membrane protein]]
[[Category: Methanogenesis]]
[[Category: Methyltransferase]]
[[Category: Motor pump]]
[[Category: Rossmann fold]]
[[Category: Transferase]]
[[Category: Vitamin b12]]