8jub: Difference between revisions
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==Crystal structure of glutaminase C in complex with compound 27== | |||
<StructureSection load='8jub' size='340' side='right'caption='[[8jub]], [[Resolution|resolution]] 2.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8jub]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JUB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=V4I:3-[2-oxidanylidene-2-[[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic+acid'>V4I</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jub OCA], [https://pdbe.org/8jub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jub RCSB], [https://www.ebi.ac.uk/pdbsum/8jub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jub ProSAT]</span></td></tr> | ||
[[Category: Hanyu | </table> | ||
[[Category: Wang | == Function == | ||
[https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hanyu S]] | |||
[[Category: Tingting D]] | |||
[[Category: Wang X]] | |||
Latest revision as of 05:59, 11 October 2023
Crystal structure of glutaminase C in complex with compound 27
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