6eem: Difference between revisions

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<StructureSection load='6eem' size='340' side='right'caption='[[6eem]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
<StructureSection load='6eem' size='340' side='right'caption='[[6eem]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6eem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Opium_poppy Opium poppy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EEM FirstGlance]. <br>
<table><tr><td colspan='2'>[[6eem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Papaver_somniferum Papaver somniferum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EEM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PR:N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-tyrosine'>0PR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6100066&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PR:N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-tyrosine'>0PR</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6eei|6eei]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tydc9 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3469 Opium poppy])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aromatic-L-amino-acid_decarboxylase Aromatic-L-amino-acid decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.28 4.1.1.28] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6eem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eem OCA], [https://pdbe.org/6eem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6eem RCSB], [https://www.ebi.ac.uk/pdbsum/6eem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6eem ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6eem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6eem OCA], [https://pdbe.org/6eem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6eem RCSB], [https://www.ebi.ac.uk/pdbsum/6eem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6eem ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYDC_PAPSO TYDC_PAPSO] Converts tyrosine into tyramine, a precursor of isoquinoline alkaloids and various amides.<ref>PMID:23204519</ref> <ref>PMID:25107664</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aromatic-L-amino-acid decarboxylase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Opium poppy]]
[[Category: Papaver somniferum]]
[[Category: Chiang, Y]]
[[Category: Chiang Y]]
[[Category: Smith, T]]
[[Category: Smith T]]
[[Category: Torrens-Spence, M P]]
[[Category: Torrens-Spence MP]]
[[Category: Vicent, M A]]
[[Category: Vicent MA]]
[[Category: Wang, Y]]
[[Category: Wang Y]]
[[Category: Weng, J K]]
[[Category: Weng JK]]
[[Category: Aromatic amino acid decarboxylase]]
[[Category: Lyase]]
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