6m7k: Difference between revisions

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<StructureSection load='6m7k' size='340' side='right'caption='[[6m7k]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
<StructureSection load='6m7k' size='340' side='right'caption='[[6m7k]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6m7k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M7K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6M7K FirstGlance]. <br>
<table><tr><td colspan='2'>[[6m7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M7K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Akr1c13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6m7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m7k OCA], [http://pdbe.org/6m7k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m7k RCSB], [http://www.ebi.ac.uk/pdbsum/6m7k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m7k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m7k OCA], [https://pdbe.org/6m7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m7k RCSB], [https://www.ebi.ac.uk/pdbsum/6m7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m7k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AK1CD_MOUSE AK1CD_MOUSE]] Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP (By similarity).  
[https://www.uniprot.org/uniprot/AK1CD_MOUSE AK1CD_MOUSE] Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Eaglesham, J B]]
[[Category: Synthetic construct]]
[[Category: King, D S]]
[[Category: Eaglesham JB]]
[[Category: Kranzusch, P J]]
[[Category: King DS]]
[[Category: Lee, A S.Y]]
[[Category: Kranzusch PJ]]
[[Category: Mann, C C.de Oliveira]]
[[Category: Lee ASY]]
[[Category: Mekalanos, J J]]
[[Category: Mekalanos JJ]]
[[Category: Morehouse, B R]]
[[Category: Morehouse BR]]
[[Category: Nieminen, E A]]
[[Category: Nieminen EA]]
[[Category: Whiteley, A T]]
[[Category: Whiteley AT]]
[[Category: Akr1c13]]
[[Category: De Oliveira Mann CC]]
[[Category: Cyclic amp-amp-gmp]]
[[Category: Innate immunity]]
[[Category: Oxidoreductase]]
[[Category: Recon]]
Retrieved from "https://proteopedia.org/6m7k"