6mo0: Difference between revisions

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<StructureSection load='6mo0' size='340' side='right'caption='[[6mo0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6mo0' size='340' side='right'caption='[[6mo0]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6mo0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MO0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MO0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6mo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MO0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JVJ:1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine'>JVJ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mo0 OCA], [http://pdbe.org/6mo0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mo0 RCSB], [http://www.ebi.ac.uk/pdbsum/6mo0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mo0 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JVJ:1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine'>JVJ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mo0 OCA], [https://pdbe.org/6mo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mo0 RCSB], [https://www.ebi.ac.uk/pdbsum/6mo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mo0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6mo0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6mo0" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dengue virus 2]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hua, Y]]
[[Category: Hua Y]]
[[Category: Huo, T]]
[[Category: Huo T]]
[[Category: Lin, Y L]]
[[Category: Lin Y-L]]
[[Category: Nie, S]]
[[Category: Nie S]]
[[Category: Song, Y]]
[[Category: Song Y]]
[[Category: Wu, F]]
[[Category: Wu F]]
[[Category: Wu, J]]
[[Category: Wu J]]
[[Category: Yao, Y]]
[[Category: Yao Y]]
[[Category: Allosteric inhibitor]]
[[Category: Complex]]
[[Category: Inhibitor]]
[[Category: Protease]]
[[Category: Viral protein]]
[[Category: Viral protein-inhibitor complex]]